I have an old Kemper Head. I have not had a chance to try QC or Fractal or Helix hardware, so I cannot tell about the difference. I read everywhere about the "Kemper sound". I have not heard it in my unit so far, maybe it is because I did not try any of the above side by side.
What I have started though is to use the Kemper via digit i/o and use my Focusrite Clarett+ IOs for guitar in and monitor out. This is in my bedroom studio only. I find it much better, and it actually sounds stellar to me. Few comparisons I tried since I have been using it like that are some plugins. Free ToneX player with factory captures, Helix AU plugin, Logic Pro X amp emulations. My verdict on sound quality: 1. Kemper, 2. ToneX, 3. Logic 4. Helix. None other than the Kemper has the harmonics as an amp has. If you play anything on the Kemper on higher notes, you hear as if the strings you play on were thicker physically. It's thick and harmonic rich.
I would be quite curious to compare the Kemper with better external preamps and converter to QC and some newer Fractal units (Axe-FX III or FM3). This would tell a lot about the real tone properties of the algorithms themselves.